The Defenders Vs. Abnegezar, Rath & Ghast and Neron

 

The Defenders seemed to spend as much time or more battling demons and supernatural threats as they did traditional super-villains.  It might be interesting to see how they would fare against the denizens of DC's underworld.

Doctor Strange and Detective Chimp

 

Mephisto has been teased in the MCU (which has led to rampant speculation) but not actually used yet, and I wonder where or if he will actually show up.  While he is a key villain from the comics with ties to many heroes, he still poses some problems when it comes to adapting him for the movies.  China does not like any depictions of Satan, so that may be giving Disney pause.  Will he appear in altered form, or will he be included with all of his devlish trappings, knowing his presence will keep the film out of a major market?  Only time will tell.