Nova and The Ray

 

With two brightly glowing heroes zipping through the cosmos, I think that this would be a visually interesting tale to depict - and a fun one to read about!

Batman Vs. Aliens (The Movie!)

 I remember a pretty well done Batman Vs. Aliens mini-series in comic book form back in the day, but how cool would a live action version of that match up been?  Get Ridley Scott or James Cameron back to direct and that would have been quite the blockbuster!